D2-40 immunoreactivity in gastric carcinoma cases. (A-B) Tumor cell emboli are observed within lymphatic vessels in a case with gastric carcinoma with diffuse lymphovascular invasion (A, H&E; B, D2-40). (C-D) Dilated lymphatic vessels are displayed in the peritumoral area in a poorly differentiated adenocarcinoma case (C, H&E; D, D2-40). Intratumoral lymphatic vessels with a narrow lumen are demonstrated in a well differentiated (E) and poorly differentiated (F) adenocarcinoma cases (E-F, D2-40).
Karadayı et al. Diagnostic Pathology 2013 8:151 doi:10.1186/1746-1596-8-151