Table 1

Clinical features of 11 cases of inflammatory myofibroblastic tumor with RANBP2-ALK gene fusion
Case Author Age Sex Anatomic site(s) Size (cm) Treatment Follow-up
1 Ma [5] (2003) 7 y Male Unspecified abdominal mass NA SE + CT Recurred 5 weeks later after first resection. A re-excision was performed. Five months later, the tumor recurred again and was re-excised.
2 7 m Male Mesentery and omentum 11 SE Recurred 8 months later after first resection. A re-excision was performed.
3 Patel [7] (2007) 2 y Male Retroperitoneal abdominal mass 10 SE No evidence of recurrence with 3 years of follow-up.
4 Chen [8] (2008) 34 y Male Liver 8 SE Recurred 5 months later after resection. Died of the disease approximately 2 weeks after discovery of the recurrence.
5 Butrynski [9] (2010) 44 y Male Omentum NA SE + CT + ALKi Hepatic, peripancreatic, and perirectal masses recurred 1 year later after resection. Subsequent exploratory laparotomy with maximal debulking was performed.
6 Marino-Enriquez [10] (2011) 41 y Male Omentum 26 SE + CT + ALKi Multifocal local recurrence and liver metastases. Alive with no evidence of disease for 40 months.
7 6 y Male Omentum and Mesentery 14 SE NA
8 39 y Male Mesentery of the small bowel 14 SE NA
9 Kozu [11] (2013) 57 y Male Pluera or chest wall NA ALKi NA
10 Present cases (2013) 19 y Female Mesentery of the small bowel 19 SE Recurred 9 weeks later after resection. Died of the disease 3 weeks later after discovery of the recurrence.
11 39 y Male Mesentery of the colon 15 SE + CT Recurred 4 months later after resection. Alive with disease for 12 months.

SE surgical excision, CT chemotherapy, ALKi ALK inhibitor, NA data not available.

Li et al.

Li et al. Diagnostic Pathology 2013 8:147   doi:10.1186/1746-1596-8-147

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