Table 5

The correlation of V-ATPase expression with drug sensitivity (resistance) in lung adenocarcinoma
V-ATPase Cyclophosphamide Gemcitabine Doxorubicin Paclitaxel Cisplatin
R LS MS HS p value R LS MS HS p value R LS MS HS p value R LS MS HS p value R LS MS HS p value
_ 0 9 4 1 χ2 = 20.68 0 2 8 4 χ2 = 21.45 0 1 6 7 χ2 = 17.47 1 0 2 11 χ2 = 15.12 2 2 6 4 χ2 = 21.04
+ 10 19 2 0 p = 0.002 3 6 20 2 p = 0.002 13 6 7 5 p = 0.008 1 0 5 25 p = 0.004 5 10 11 7 p = 0.002
++ 4 0 0 0 rs = −0.584 2 2 0 0 rs = −0.512 2 2 0 0 rs = −0.544 2 0 2 0 rs = −0.269 4 0 0 0 rs = −0.306

R: Resistance; LS: Low sensitivity; MS: Moderate sensitivity; HS: High sensitivity.

Lu et al.

Lu et al. Diagnostic Pathology 2013 8:145   doi:10.1186/1746-1596-8-145

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