Table 2

Main results of pooled odds ratios (ORs) with confidence interval (CI) in the meta-analysis
Variables No. of studies Ser/Ser vs Cys/Cys Ser/Ser vs Ser/Cys Ser/Cys vs Cys/Cys
OR (95% CI) Ph P OR (95% CI) Ph P OR (95% CI) Ph P
Total 30 0.885(0.765 1.024) 0.002 0.101 0.982(0.898 1.075) 0.023 0.698 0.909(0.802 1.029) 0.006 0.131
Ethnicity
Asian 17 0.850(0.732 0.986) 0.064 0.032 0.973(0.860 1.100) 0.102 0.659 0.887(0.771 1.020) 0.012 0.092
Caucasian 13 0.946(0.683 1.310) 0.005 0.738 0.993(0.866 1.138) 0.041 0.915 0.970(0.734 1.281) 0.070 0.829
Source of controls
PB 14 0.993(0.810 1.216) 0.069 0.945 0.974(0.877 1.083) 0.377 0.630 0.956(0.833 1.098) 0.367 0.527
HB 16 0.798(0.649 0.982) 0.007 0.033 0.991(0.858 1.144) 0.007 0.900 0.837(0.689 1.017) 0.001 0.073
Variables No. of studies Ser/Ser + Ser/Cys vs Cys/Cys (dominant) Ser/Ser vs Ser/Cys + Cys/Cys (recessive) Ser allele vs Cys allele
OR (95% CI) Ph P OR (95% CI) Ph P OR (95% CI) Ph P
Total 30 0.133(0.111 0.161) 0.000 0.000 0.543(0.399 0.739) 0.000 0.000 0.947(0.880 1.019) 0.000 0.143
Ethnicity
Asian 17 0.160(0.137 0.187) 0.001 0.000 0.875(0.684 1.118) 0.000 0.285 0.931(0.865 1.000) 0.064 0.052
Caucasian 13 0.101(0.069 0.147) 0.000 0.000 0.300(0.198 0.454) 0.000 0.000 0.970(0.836 1.125) 0.000 0.686
Source of controls
PB 14 0.143(0.111 0.184) 0.000 0.000 0.429(0.261 0.705) 0.000 0.001 0.979(0.897 1.069) 0.087 0.644
HB 16 0.122(0.091 0.163) 0.000 0.000 0.670(0.455 0.986) 0.000 0.042 0.916(0.817 1.026) 0.000 0.131

Ph P value of heterogeneity.

Xu et al.

Xu et al. Diagnostic Pathology 2013 8:144   doi:10.1186/1746-1596-8-144

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