Table 1

Main characteristics of these studies included in this meta-analysis
First author [Inference] Year Country Ethnicity Control source Cases Controls PHWE
Ser/Ser Ser/Cys Cys/Cys Ser/Ser Ser/Cys Cys/Cys
Kohno 1998 Japan Asian PB 16 19 10 15 20 7 0.93
Le Marchand a 2002 USA Caucasian PB 78 39 9 98 53 8 0.81
Le Marchand b 2002 USA Asian PB 30 40 27 50 74 26 0.88
Lan 2004 China Asian PB 37 61 20 51 43 15 0.23
Vogel 2004 Denmark Caucasian PB 149 93 14 159 91 19 0.24
Loft 2006 Denmark Caucasian PB 144 93 14 154 88 19 0.20
Matullo 2006 Italy Caucasian PB 66 46 4 673 371 50 0.90
Sorensen 2006 Denmark Caucasian PB 254 155 22 479 284 33 0.26
Zienolddiny 2006 Italy Caucasian PB 182 100 44 194 117 75 0.01
Hatt 2008 Denmark Caucasian PB 92 58 8 93 59 12 0.54
Karahalil 2008 Turkey Caucasian PB 86 65 14 115 106 29 0.55
Okasaka 2009 Japan Asian PB 117 257 141 250 544 236 0.07
Li 2011 China Asian PB 83 208 164 60 219 164 0.33
Qian 2011 China Asian PB 100 288 193 125 291 185 0.59
Sugimura 1999 Japan Asian HB 85 115 41 63 107 27 0.08
Wikman 2000 Germany Caucasian HB 68 32 5 60 43 2 0.07
Ito 2002 Japan Asian HB 40 71 27 68 118 54 0.84
Sunaga 2002 Japan Asian HB 54 106 38 50 66 36 0.13
Park 2004 USA Caucasian HB 101 65 13 255 87 8 0.86
Hung 2005 European Caucasian HB 1401 661 93 1368 716 79 0.22
Liang 2005 China Asian HB 27 132 68 28 123 76 0.04
Wang 2005 China Asian HB 49 51 24 45 70 13 0.06
Kohno 2006 Japan Asian HB 285 544 268 123 190 81 0.63
De Ruyck 2007 Belgium Caucasian HB 74 33 3 60 46 4 0.18
Chang 2009 China Asian HB 142 518 436 154 482 361 0.74
Gao 2009 China Asian HB 27 35 24 30 49 11 0.19
Miyaishi 2009 Japan Asian HB 27 55 26 39 54 28 0.27
Liu 2010 China Asian HB 68 158 132 110 294 312 0.01
Janik 2011 Poland Caucasian HB 48 24 16 57 21 1 0.54
Kohno 2011 Japan Asian HB 115 162 100 98 164 63 0.70

a,b Two different ethnicity studies in one publication. PB Population-Based Study, HB Hospital-Based Study, PHWE P value of Hardy–Weinberg Equilibrium.

Xu et al.

Xu et al. Diagnostic Pathology 2013 8:144   doi:10.1186/1746-1596-8-144

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