Evaluation of accuracy of fine needle aspiration cytology and histopathology for diagnosis of feline mammary tumours. A: Malignant multinucleated mammary epithelial cell; nuclei exhibit nuclear criteria of malignancy; nuclei super imposed and in different focal planes. May-Grunwald-Giemsa staining method, 1000X. B: Cells exhibit variable numbers of mitoses are found; or the second populationof cells may have oval to fusiform vesicular nuclei with an extensive amount of eosinophilic cytoplasm and distinc cell margins (H&E, X 400). C: Solid adenocarcinoma; The presence of neoplastic, mitotic and inflammatory cells (H&B, X 200.), D: Hemorrhage foci and the central necrotic areas are interpreted as an indication that the neoplastic cells are growing faster and that there is therefore a higher risk of progressionto invasive carcinoma (H&E, X100).
Shafiee et al. Diagnostic Pathology 2013 8:136 doi:10.1186/1746-1596-8-136