Table 4

STAT5 siRNA induced the apoptosis and suppressed invasion and metastasis of Eca-109
Group Transfected vector The cell apoptosis rate (%) The average amount of cells per field
STAT5 siRNA pRNAT-U6.1/Neo -siSTAT5 13.38 ± 1.87* 24.2 ± 5.1*
siRNA control pRNAT-U6.1/Neo-siCon 4.76 ± 0.69 65.2 ± 10.4
The blank control - 4.49 ± 0.73 71.9 ± 12.4

The average apoptosis rate of Eca-109 cell transfected with STAT5 siRNA was significantly increased (*p < 0.05), The average amount of cells penetrating Matrigel was significantly suppressed (*p < 0.05).

Yang et al.

Yang et al. Diagnostic Pathology 2013 8:132   doi:10.1186/1746-1596-8-132

Open Data