Table 2

STAT5 siRNA inhibited significantly the mRNA expression of STAT5、Bcl-2 and Cyclin D1
Group n STAT5/GAPDH Bcl-2/GAPDH Cyclin D1/GAPDH
STAT5 siRNA 4 0.301 ± 0.012* 0.266 ± 0.012* 0.048 ± 0.005*
siRNA control 4 0.836 ± 0.038 0.645 ± 0.023 0.261 ± 0.013
The blank control 4 0.857 ± 0.041 0.687 ± 0.027 0.273 ± 0.012

Cells were incubated with different synthetic oligonucleotides as described in the materials and methods section, and STAT5、Bcl-2 and Cyclin D1mRNA were quantified by real time PCR. The targeted STAT5 siRNA inhibited significantly the expression of STAT5、Bcl-2 and Cyclin D1 gene (*p <0.05).

Yang et al.

Yang et al. Diagnostic Pathology 2013 8:132   doi:10.1186/1746-1596-8-132

Open Data