Table 3

Correlation between nuclear, cytoplasmic CARM1 expression and molecular subtypes of breast cancer patients
Molecular subtypes n Nuclear CARM1 expression P Cytoplasmic CARM1 expression P
Negative or low expression (IHC score < 80) High or over expression (IHC score ≥ 80) Negative or low expression (IHC score < 80) High or over expression (IHC score ≥ 80)
Lumina A 121 71 (58.7) 50 (41.3) 0.019 60 (49.6) 61 (50.4) 0.066
Luminal B 47 19 (40.4) 28 (59.6) 19 (40.4) 28 (59.6)
HER2 type 23 7 (30.4) 16 (69.6) 5 (21.7) 18 (78.3)
triple negative 56 24 (42.9) 32 (57.1) 21 (37.5) 35 (62.5)

P value is the result of χ2 test in the same factor, and < 0.05 is considered statistically significant.

Cheng et al.

Cheng et al. Diagnostic Pathology 2013 8:129   doi:10.1186/1746-1596-8-129

Open Data