A) Histologically the tumor was composed of nodules of polygonal epithelioid and spindle cells circumscribe areas of central hyalinization and necrosis (H&E, ×200). B) The nodular pattern was composed by large cells with amphophilic cytoplasm. The tumor nodules were surrounded by and infiltrated by inflammatory cells. Nuclei were large and vescicolar and nucleoli were overshot (H&E, ×200). C) Immunostaining showed KERAE1-AE3+, VIM+, EMA-, CD34- ker 5-6-, s100-, ACTml-, MART1-, HMB45- (H&E, ×200).
Patrizi et al. Diagnostic Pathology 2013 8:122 doi:10.1186/1746-1596-8-122