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Open Access Case Report

Atypical florid vascular proliferation in appendix: a diagnostic dilemma

Mi Jin Gu1*, Joon Hyuk Choi1 and So Hyun Kim2

Author affiliations

1 Department of Pathology, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu, Rep of Korea

2 Department of Surgery, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu, Rep of Korea

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Citation and License

Diagnostic Pathology 2013, 8:12  doi:10.1186/1746-1596-8-12

Published: 24 January 2013

Abstract

Vascular abnormality of the intestine is rare, except angiodysplasia. We report on an unusual case of atypical florid vascular proliferations of the appendix. A 41-year old male presented with melena. Adhesioned blood clots in the appendiceal orifice were observed by colonoscopy. He underwent laparoscopic appendectomy. Microscopically, a tiny exophytic polypoid mass was observed. The mass showed pyogenic granuloma-like features in the superficial portion and infiltrative florid vascular proliferations in the deeper portion. Endothelial cells showed minimal nuclear atypia, and mitotic figures were observed infrequently and showed positivity for CD31 and CD34 and negativity for HHV-8. Differential diagnoses include from benign vascular tumor to angiosarcoma or Kaposi’s sarcoma, but this lesion does not fit the description of any defined vascular entity. We diagnosed atypical florid vascular proliferations and the patient has been well during the five-month postoperative follow-up.

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Keywords:
Blood vessel; Proliferation; Atypical; Appendix