Morphology of this renal tumor. (A) Macroscopic appearance of the tumor. A global firm grayish yellowish tumor in the upper part of kidney and near hilus renalis, involving the renal medulla and the cortex. (B) Histological feature of the tumor showed large areas of geographic coagulative necrosis of kidney (H&E × 100). (C) Tubules or angulated glands irregularly infiltrating the renal parenchyma with a prominent interstitial growth pattern (H&E × 200). (D) Tumor cells with abundant eosinophilic cytoplasm and large hyperchromatic nuclei with prominent nucleoli (H&E × 400). (E) Hobnail nuclei were noted in the fibrous background (H&E × 400). (F) Microabscess like necrosis was occasionally seen with scattered atypical cells (H&E × 400).
Xu et al. Diagnostic Pathology 2013 8:119 doi:10.1186/1746-1596-8-119