Table 1

Main characteristics of these studies included in this meta-analysis
First author Year Country Ethnicity Genotype method Cases Controls HWE
Pro/ Pro Ala-carrier Pro/ Pro Ala-carrier
Mori et al. 2001 Japanese Asian PCR-RFLP 580 28 982 42 Yes
Herrmann et al. 2002 German Caucasian PCR-RFLP 154 43 144 59 Yes
Caramori et al. 2003 Brazilian Caucasian PCR-RFLP 93 11 169 43 Yes
Wu et al. 2004 Chinese Asian PCR-RFLP 194 26 102 6 Yes
Maeda et al. 2004 Japanese Asian PCR-RFLP 46 15 55 24 Yes
Pollex et al. 2007 Canadian Caucasian PCR-RFLP 94 3 55 7 Yes
Erdogan et al. 2007 Turk Asian PCR-RFLP 43 0 47 1 Yes
Wei et al. 2008 Chinese Asian PCR-RFLP 68 14 89 10 Yes
Li et al. 2008 Chinese Asian PCR 150 15 77 17 Yes
Wu et al. 2009 Taiwanese Asian Taqman 157 18 197 17 Yes
De Cosmo et al. 2009 Italian Caucasian Taqman 86 7 856 170 Yes
Liu et al. 2010 Chinese Asian PCR-RFLP 499 33 199 29 Yes
Lapice et al. 2010 Italian Caucasian PCR-RFLP 53 2 606 89 Yes
Zhu et al. 2011 Chinese Asian PCR-RFLP 39 2 33 4 Yes
De Cosmo et al1 2011 Italian Caucasian SBE 221 40 499 81 Yes
De Cosmo et al2 2011 Italian Caucasian Taqman 224 30 316 53 Yes
De Cosmo et al3 2011 Italian Caucasian ASA 207 25 422 60 Yes
Zhang et al. 2012 Indian Asian PCR-RFLP 113 28 206 49 Yes

PCR-RFLP: Polymerase Chain Reaction-Restriction Fragment Length Polymorphism; PCR: Polymerase Chain Reaction; SBE: Single-Base Extension; ASA: Allele-Specific Amplification; 1,2,3: Different studies in one publication; HWE: Hardy–Weinberg Equilibrium; Yes: PHWE value>0.05.Reaction; SBE: Single-Base Extension; ASA: Allele-Specific Amplification; 1,2,3: Different studies in one publication; HWE: Hardy–Weinberg Equilibrium; Yes: PHWE value>0.05.

Wang et al.

Wang et al. Diagnostic Pathology 2013 8:118   doi:10.1186/1746-1596-8-118

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