Table 1

Morphology and immunophenotype of 25 breast carcinomas in situ with mixed pattern analyzed from breast biopsies
Morphological pattern of in situ lesion Morphology of in situ lesion with mixed pattern E-cadherin immunophenotype β-catenin immunophenotype
Case # Lobular Ductal Mixed Nuclear pleomorphism Comedonecrosis Mixed cytology or architecture Lobular areas Ductal areas Lobular areas Ductal areas
1 Yes Yes Yes No No Yes - + - +
2 No No Yes No No Yes - + - +
3 No No Yes No No Yes + + + +
4 No No Yes No No Yes + + + +
5 No No Yes Yes No No - + - +
6 No No Yes No No Yes + + + +
7 Yes No Yes No No Yes + + + +
8 No No Yes No No Yes + + + +
9 No No Yes Yes Yes No - + - +
10 No No Yes No No Yes - + - +
11 No Yes Yes No No Yes + + + +
12 No No Yes No No Yes + + NA NA
13 No No Yes Yes Yes No - - - -
14 Yes Yes Yes No No Yes - + - +
15 No Yes Yes No No Yes + + + +
16 No No Yes Yes No Yes - + NA NA
17 Yes No No Yes No Yes - + - +
18 Yes Yes Yes No No Yes - + NA NA
19 No Yes Yes No No Yes + + + +
20 No No Yes No No Yes + + + +
21 No No Yes No No Yes - + - +
22 Yes Yes Yes No No Yes - + NA NA
23 No No Yes No No Yes - + - +
24 No No Yes Yes No No - + NA NA
25 No Yes Yes No No Yes + + + +

NA Not applied.

Gomes et al.

Gomes et al. Diagnostic Pathology 2013 8:114   doi:10.1186/1746-1596-8-114

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