Case # 8: Carcinoma in situ with mixed pattern (CISM) showing dual cell population (Group 2) stained for hematoxylin and eosin (A – 100×, B – 400×). A stronger positive membrane staining for E-cadherin (C – 400×) and β-catenin (D – 400×) can be appreciated in the outer layer of cells of ductal pattern. A weaker staining is seen in cells of lobular pattern present in the center of the units.
Gomes et al. Diagnostic Pathology 2013 8:114 doi:10.1186/1746-1596-8-114