The histopathologic changes of nude mice tumor tissues. The histopathologic changes of tumor tissues from two nude mice models bearing esophageal carcinoma were observed using HE stains. The tumor cells in group CXCR4 siRNA1 and CXCR4 siRNA2 had apoptosis and necrosis, morphology was different from each other, nuclei showed pathological division and the giant tumor cells were rare (400 x).
Wang et al. Diagnostic Pathology 2013 8:104 doi:10.1186/1746-1596-8-104