Table 3 |
||||||
| Positive likelihood ratio (Positive LR) and negative likelihood ratio (Negative LR) of each immunohistochemistry marker and association | ||||||
| IHC ANALYSIS | Positive LR (95% CI) | Q | P | Negative LR (95% CI) | Q | P |
| CK-19 [10,14-33] | 2.87 (2.10-3.92) | 262.28 | <0.00001 | 0.25 (0.18-0.35) | 131.17 | <0.00001 |
| GAL-3 [10,14-17,19,21,25-56] | 4.24 (3.08-5.82) | 605.28 | <0.00001 | 0.21 (0.15-0.30) | 508.27 | <0.00001 |
| HBME-1 [10,14-19,21,24-27,29,30,41,51,57-61] | 6.93 (4.42-10.88) | 355.63 | <0.00001 | 0.22 (0.16-0.30) | 234.36 | <0.00001 |
| CK-19 + HBME-1 [14,17] | 16.71 (0.38-742.57) | 6.35 | 0.0118 | 0.16 (0.10-0.25) | 0.11 | 0.7385 |
| GAL-3 + CK-19 [14,17] | 8.49 (1.04-69.17) | 6.83 | 0.0089 | 0.10 (0.05-0.19) | 0.15 | 0.6943 |
| GAL-3 + HBME-1 [14,17,46,51] | 4.92 (1.70-14.27) | 13.48 | 0.0037 | 0.23 (0.03-1.70) | 107.69 | <0.00001 |
| GAL-3 + HBME-1 + CK-19 [14,17,29] | 17.19 (3.36-87.96) | 3.69 | 0.1577 | 0.17 (0.11-0.24) | 0.10 | 0.9508 |
de Matos et al. Diagnostic Pathology 2012 7:97 doi:10.1186/1746-1596-7-97
