Table 3

Positive likelihood ratio (Positive LR) and negative likelihood ratio (Negative LR) of each immunohistochemistry marker and association
IHC ANALYSIS Positive LR (95% CI) Q P Negative LR (95% CI) Q P
CK-19 [10,14-33] 2.87 (2.10-3.92) 262.28 <0.00001 0.25 (0.18-0.35) 131.17 <0.00001
GAL-3 [10,14-17,19,21,25-56] 4.24 (3.08-5.82) 605.28 <0.00001 0.21 (0.15-0.30) 508.27 <0.00001
HBME-1 [10,14-19,21,24-27,29,30,41,51,57-61] 6.93 (4.42-10.88) 355.63 <0.00001 0.22 (0.16-0.30) 234.36 <0.00001
CK-19 + HBME-1 [14,17] 16.71 (0.38-742.57) 6.35 0.0118 0.16 (0.10-0.25) 0.11 0.7385
GAL-3 + CK-19 [14,17] 8.49 (1.04-69.17) 6.83 0.0089 0.10 (0.05-0.19) 0.15 0.6943
GAL-3 + HBME-1 [14,17,46,51] 4.92 (1.70-14.27) 13.48 0.0037 0.23 (0.03-1.70) 107.69 <0.00001
GAL-3 + HBME-1 + CK-19 [14,17,29] 17.19 (3.36-87.96) 3.69 0.1577 0.17 (0.11-0.24) 0.10 0.9508

de Matos et al.

de Matos et al. Diagnostic Pathology 2012 7:97   doi:10.1186/1746-1596-7-97

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