Table 2

Sensitivity and specificity of each immunohistochemistry marker or association
IHC ANALYSIS Sensitivity (95% CI) Q P Specificity (95% CI) Q P
CK-19 [10,14-33] 0.81 (0.79-0.83) 192.02 <0.00001 0.73 (0.70-0.75) 254.49 <0.00001
GAL-3 [10,14-17,19,21,25-56] 0.82 (0.81-0.84) 341.95 <0.00001 0.81 (0.79-0.82) 512.70 <0.00001
HBME-1 [10,14-19,21,24-27,29,30,41,51,57-61] 0.77 (0.76-0.79) 298.64 <0.00001 0.83 (0.82-0.85) 444.58 <0.00001
CK-19 + HBME-1 [14,17] 0.86 (0.77-0.92) 0.41 0.5245 0.97 (0.89-1.00) 7.46 0.0063
GAL-3 + CK-19 [14,17] 0.91 (0.83-0.96) 0.01 0.9383 0.91 (0.81-0.97) 5.31 0.0212
GAL-3 + HBME-1 [14,17,46,51] 0.75 (0.67-0.81) 57.91 <0.00001 0.89 (0.82-0.94) 7.46 0.0587
GAL-3 + HBME-1 + CK-19 [14,17,29] 0.85 (0.78-0.90) 0.25 0.8826 0.97 (0.90-0.99) 7.33 0.0256

de Matos et al.

de Matos et al. Diagnostic Pathology 2012 7:97   doi:10.1186/1746-1596-7-97

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