Immunohistochemistry of N-cadherin expression in papillary RCC. Papillary RCC type II with high nuclear polymorphism and abundant cytoplasm of the tumor cells (A, x20) displays a strong membranous expression of N-cadherin (B, x40). Papillary RCC type I with a single layer of cuboidal cells and a small cytoplasmic rim (C, x20) shows only a weak cytoplasmic N-cadherin (D, x40).
Behnes et al. Diagnostic Pathology 2012 7:95 doi:10.1186/1746-1596-7-95