Table 1 |
|||
| Demographic and Clinic-pathological features of the subjects under study | |||
| Variable | CTR | COPD | LC |
| (N = 33) | (N = 23) | (N = 26) | |
| Age (y) | 55 (23–82) 2 | 66 (41–85)2 | 66 (25–87)2 |
| Male (%) | 15 (45) | 10 (44) | 18 (69) |
| Female (%) | 18 (54) | 13 (56) | 8 (31) |
| Smoking history (%) | |||
| Never smoker | 33 (100) | 0 (0) | 8 (31) |
| Ex-smokers | 0 (0) | 7 (30) | 7 (27) |
| Smokers | 0 (0) | 16 (70) | 11 (42) |
| Smoking Frequency (%) | |||
| < 35 cigarette pack | 0 | 18 (78) | 10 (56) |
| ≥ 35 cigarette pack | 0 | 5 (22) | 8 (44) |
| COPD by Spirometry (%) | |||
| GOLD 0 | - | 4 (17) | 7 (27) |
| GOLD 1 | - | 5 (22) | 1 (4) |
| GOLD 2 | - | 5 (22) | 12 (46) |
| GOLD 3 | - | 8 (35) | 5 (19) |
| GOLD 4 | 1 (4) | 1 (4) | |
| Histology (%) | - | - | |
| NSCLCs | - | - | 25 (96) |
| -SCC | - | - | 6 (23) |
| -AD | - | - | 6 (23) |
| -LCLC | - | - | 13 (50) |
| SCLC | 1 (100) | ||
| Cytological analysis (%) | |||
| Normal cells | 29 (88)3 | 5 (22) | 8 (31) |
| Inflammatory cells | 4 (12) | 18 (78) | 3 (12) |
| Atypia cellular4 | - | - | 6 (23) |
| CIS (cancer cells)5 | - | - | 12 (46) |
| Sputum DNA (ng/mL) | 2.75 (0.00-4.95)6 | 15.95 (8.25-20.35)7 | 20.35 (4.95-28.60) |
1 Statistical comparisons are between cases (COPD, LC) and CTR.
2 Median (minimum and maximum).
3 p < 0.05 compared with COPD.
4 Atypia cells (was classified from mild to severe.
5 CIS = Carcinoma in situ.
6 p < 0.0001 compared with COPD and LC.
7p > 0.05 compared with LC.
Guzmán et al. Diagnostic Pathology 2012 7:87 doi:10.1186/1746-1596-7-87
