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Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokers

Leda Guzmán*, María Soledad Depix, Ana María Salinas, Rosa Roldán, Francisco Aguayo, Alejandra Silva and Raul Vinet

Diagnostic Pathology 2012, 7:87  doi:10.1186/1746-1596-7-87

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