Table 2

EZH2 staining
EZH2 expression Negative (score0) Weak (score1) Moderate (score2) Strong (score3) Sensitivity/Specificity
Hepatocellular carcinoma (n = 44) 0.90/0.33
 Grade I. 2 6 4 0
 Grade II. 1 12 7 2
 Grade III 1 4 2 2
 Grade IV. 0 1 0 0
CC (n = 23) 0.96/0.18
 Grade I. 0 2 2 1
 Grade II. 1 2 9 2
 Grade III 0 1 3 0
Hepatoblastoma (n = 31) 2 6 9 14 0.94/0.24
Hepatocellular adenoma (n = 24) 24 0 0 0 0/0
Biliary cystadenoma (n = 3) 3 0 0 0 0/0
Metastases NC*
 Colon (n = 8) 0 0 5 3
 Breast (n = 2) 0 0 2 0
 Lung (n = 2) 0 0 0 2
 Neuroendocrine (n = 3) 3 0 0 0
 Urothel (n = 1) 1
 Pancreas (n = 1) 1
Childhood tumors NC*
 Rhabdomyosarcoma (n = 4) 0 1 2 1
 Neuroblastoma (n = 5) 0 0 3 2
 Wilms’ tumor (n = 5) 0 1 1 3
 Rhabdoid tumor (n = 2) 0 0 1 1
Non tumorous lesions
High grade dysplastic nodule (n = 15) 15 0 0 0
Biliary hamartoma (n = 3) 3 0 0 0
Caroli’s disease (n = 3) 3 0 0 0

*NC not counted due to low case number.

Hajósi-Kalcakosz et al.

Hajósi-Kalcakosz et al. Diagnostic Pathology 2012 7:86   doi:10.1186/1746-1596-7-86

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