Figure 5.

Immunohistochemical staining of a needle biopsy containing prostatic carcinoma with the three-marker cocktail. Malignant glands show a brown granular cytoplasmic staining pattern for AMACR with loss of basal epithelia cells (left-hand side). A limited area of benign glandular tissue can be seen on the right-hand side, showing preserved basal epithelial cells with dark brown p63 nuclear staining and red CK5 cytoplasmic staining (x 400).