Table 2

Correlation of clinicopathological parameters with fascin and CD44v6 expressions in 47 endometrioid carcinoma
Variables Fascin CD44v6
Absent n = 13 (%) IHS ≤ 10 n = 27 (%) IHS ≥ 11 n = 7 (%) P value Absent n = 25 (%) IHS ≤ 10 n = 19 (%) IHS ≥ 11 n = 3 (%) P value
Mass size
≤4 7 (53.8%) 13 (48.1%) 3 (42.9%) 0.889 12 (48.0%) 9 (47.4%) 2 (66.7%) 0.814
≥5 6 (46.2%) 14 (51.9%) 4 (57.1%) 13 (52.0%) 10 (52.6%) 1 (33.3%)
Grade
G1 9 (69.2%) 7.(25.9%) 0 (0%) 0.003 11 (44.0%) 5 (26.3%) 0 (0%) 0.322
G2 3 (23.1%) 11 (40.7%) 2.(28.6%) 7 (28.0%) 8 (42.1%) 1.(33.3%)
G3 1 (7.7%) 9 (33.3%) 5 (71.4%) 7 (28.0%) 6 (31.6%) 2 (27.7%)
Depth of MI
Absent 2 (15.4%) 0 (0%) 0 (0%) 0.244 2 (8.0%) 0 (0%) 0 (0%) 0.527
Superficial 5 (38.5%) 13 (48.1%) 3 (42.9%) 10 (40.0%) 9 (47.4%) 2 (66.7%)
Deep 6 (46.2%) 14 (51.9%) 4 (57.1%) 13 (52.0%) 10 (52.6%) 1 (33.3%)
LVI
Absent 9 (69.2%) 17 (63.0%) 2 (28.6%) 0.182 13 (52.0%) 12 (63.2%) 3 (100.0%) 0.150
Present 4 (30.8%) 10 (37.0%) 5 (71.4%) 12 (48.0%) 7 (36.8%) 0 (0%)
NI
Absent 11(84.6%) 26 (96.3%) 4 (57.1%) 0.036 22 (88.0%) 16 (84.2%) 3 (100.0%) 0.613
Present 2 (15.4%) 1 (3.7%) 3 (42.9%) 3 (12.0%) 3 (15.8%) 0 (0%)
Stage
1 8 (61.5%) 18 (66.7%) 3 (42.9%) 0.597 17 (68.0%) 10 (52.6%) 2 (66.7%) 0.084
2 3 (23.1%) 6 (22.2%) 2 (28.6%) 3 (12.0%) 8(42.1%) 0 (0%)
3 1 (7.7%) 2 (7.4%) 0 (0%) 2 (8.0%) 0 (0%) 1 (33.3%)
4 1 (7.7%) 1 (3.7%) 2 (28.6%) 3 (12.0%) 1 (5.3%) 0 (0%)

IHS: immunohistochemical score, MI: myometrial invasion, LVI: lymphovascular invasion, NI: neural invasion.

Gun et al.

Gun et al. Diagnostic Pathology 2012 7:80   doi:10.1186/1746-1596-7-80

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