Table 2

Summary of methyaltion conditions and immunoreactivity of 18 patients with primary and recurrent gliomas

Cases

HT

DNMT

EGFR

MGMT

PGL

RGL

PGL

RGL

PGL

RGL

1

A2 → A3

2

A2 → A3

-

-

3

A3 → A3

-

-

4

A2 → A3

-

-

-

-

5

A2 → A3

+

-

-

6

A2 → A3

7

A3 → GB

-

-

-

-

-

-

8

A3 → GB

-

-

-

-

-

-

9

A3 → GB

-

-

-

10

A3 → GB

-

-

-

-

-

-

11

GB → GB

-

-

-

-

12

GB → GB

-

-

-

-

-

-

13

GB → GB

-

-

-

14

GB → GB

-

-

-

-

15

GB → GB

-

-

16

GB → GB

-

-

17

GCGB → GCGB

18

GCGB → GCGB

Abbreviations: no mark, hypermethylation; oval mark, unmethylation; PGL, primary glioma; RGL, recurrent glioma;HT, histological tranformation; A2, diffuse astrocytoma; A3, anaplastic astrocytoma; GB, glioblastoma; GCGB, giant cell glioblastoma; + positive immunoreactivity; - negative immunoreactivity

Gömöri et al. Diagnostic Pathology 2012 7:8   doi:10.1186/1746-1596-7-8