Table 4

Variance in preoperative clinicopathological parameters between patients with and without peruneural invasion (PNI)

PNI present

(n = 63)

PNI absent

(n = 61)

Univariate Multivariate
P value P value Adjusted odds ratio (95% CI)
Mean age [years] 63.7 ± 5.0 64.0 ± 5.0 0.894
PSA [ng/ml] 9.5 ± 5.9 8.5 ± 8.5 0.104
Gleason score at biopsy 7.4 ± 1.1 6.7 ± 0.9 <0.001 0.001 1.983 (1.342-2.929)
cT stage (n) 0.615
T1c 49 (77.8%) 50 (82.0%)
T2 9 (14.3%) 9 (14.8%)
T3a 5 (7.9%) 2 (3.3%)
%positive cores 23.5 ± 18.7 19.8 ±14.8 0.513
TZ biopsy positive (n) 24 (38.1%) 18 (29.5%) 0.312
Number of apex-positive (2–4/0–1) (n) 14/49 15/46 0.755
Number of middle-positive (2–4/0–1) (n) 21/42 13/48 0.134
Number of base-positive (2–4/0–1) (n) 17/46 10/51 0.153

PSA, prostate-specific antigen; TZ, transition zone; apex, prostatic apex biopsy; middle, prostatic middle biopsy; base, prostatic base biopsy.

Ishizaki et al.

Ishizaki et al. Diagnostic Pathology 2012 7:68   doi:10.1186/1746-1596-7-68

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