Table 3

Variance in preoperative clinicopathological parameters between patients with and without positive surgical margin (PSM)

PSM present

(n = 39)

PSM absent

(n = 81)

Uniivariate Multivariate
p-value P value Adjusted odds ratio (95% CI)
Mean age [years] 63.5 ± 36.0 64.0 ± 4.6 0.993
PSA [ng/ml] 9.8 ± 6.3 8.7 ± 7.8 0.247
Gleason score at biopsy 7.2 ± 1.2 7.0 ± 1.0 0.209
cT stage (n) 0.347
T1c 30 (76.9%) 65 (80.2%)
T2 5 (12.8%) 13 (16.0%)
T3a 4 (10.3%) 3 (3.7%)
%positive cores 31.0 ± 21.3 21.3 ±16.4 0.001 0.001 1.044 (1.019-1.070)
TZ biopsy positive (n) 17 (43.6%) 24 (29.6%) 0.131
Number of apex-positive (2–4/0–1) (n) 14/25 15/66 0.037
Number of middle-positive (2–4/0–1) (n) 17/22 15/66 0.004
Number of base-positive (2–4/0–1) (n) 13/26 14/67 0.049

PSA, prostate-specific antigen; TZ, transition zone; apex, prostatic apex biopsy; middle, prostatic middle biopsy; base, prostatic base biopsy. Data not available in 4 patients.

Ishizaki et al.

Ishizaki et al. Diagnostic Pathology 2012 7:68   doi:10.1186/1746-1596-7-68

Open Data