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Open Access Case Report

A case of Arrhythmogenic right ventricular cardiomyopathy without arrhythmias

Jia Wei1, Jiarong Tang1*, Liming Xia2, Xinshan Chen3 and Dao Wen Wang1

Author Affiliations

1 Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie-Fang Ave, Wuhan 430030, China

2 Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

3 Department of Forensic Pathology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

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Diagnostic Pathology 2012, 7:67  doi:10.1186/1746-1596-7-67

Published: 12 June 2012

Abstract

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by recurrent coma, ventricular tachycardias and the replacement of the myocardium with fatty and fibrous tissue. We described a 42-year-old female patient without clinical arrhythmias which was diagnosed as ARVC by magnetic resonance imaging (MRI), but the transvenous endomyocardial biopsy was not specific. The patient received heart transplantation due to her refractory heart failure and the pathology of explanted heart demonstrated typical replacement of fatty and fibrous tissue and piles of infiltrated lymphocytes in myocardial tissue. It is concluded that ARVC might not have any arrhythmias and inflammatory process may be involved in the mechanism of ARVC.

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Keywords:
Arrhythmogenic; Right ventricle cardiomyopathy; Magnetic resonance imaging; Heart transplantation