Table 2 |
|||
| Subjects’ demographic and clinical characteristics | |||
| Variables | Healthy controls (n = 47) | COPD patients (n = 47) | P-value |
| Age (years) † | 58.8 ± 4.6 | 61.3 ± 4.5 | 0.011* |
| Sex‡ | 1.000 | ||
| Males | 40 (85.1%) | 40 (85.1%) | |
| Females | 7 (14.9%) | 7 (14.9%) | |
| Smokers‡ | 24 (51.1%) | 24 (51.1%) | 1.000 |
| Smoking history (pack/year) § | 31.9 ± 7.4 | 31.7 ± 6.0 | 0.755 |
| FEV1/FVC %†, § | 86.6 ± 4.5 | 56.8 ± 5.3 | <.001* |
| FEV1,% Reference†, § | 103.1 ± 9.5 | 59.4 ± 6.3 | <.001* |
| ISAB as needed‡ | 0 (0) | 30 (63.8) | - |
| ILAB regularly‡ | 0 (0) | 18 (38.3) | - |
Abbreviations: COPD: chronic obstructive pulmonary disease; ISAB: inhaled short-acting bronchodilators; ILAB: inhaled long-acting bronchodilators.
†,‡,§ Results are means ± SDs for †,§continuous variables and n (%) for ‡categorical variables.
†‡§ Groups were compared using †two-sample t-test or §Mann–Whitney U test if data were not normally distributed. ‡Pearson Chi-square test was used for categorical variables.
* P < 0.05, significantly different between groups.
Zhang et al. Diagnostic Pathology 2012 7:65 doi:10.1186/1746-1596-7-65