Figure 3.

Correlations between mRNA levels of Bak, Bcl-xl, and Mcl-1 and lung function parameters. COPD patients are represented by solid circles and healthy controls by open circles (N = 47 for each group) Spearman correlation analysis was used to assess associations between variables. (A) Bak mRNA level was positively correlated with lung function. FEV1/FVC%: r = 0.72; P < 0.001; FEV1% reference: r = 0.70; P < 0.001. (B) Bcl-xl mRNA level was negatively correlated with lung function. FEV1/FVC%: r = -0.82; P < 0.001; FEV1% reference: r = -0.86; P < 0.001. (C) Mcl-1 mRNA level was negatively correlated with lung function. FEV1/FVC%: r = -0.79; P < 0.001; FEV1% reference: r = -0.79; P < 0.001.

Zhang et al. Diagnostic Pathology 2012 7:65   doi:10.1186/1746-1596-7-65
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