Table 2

Association of survivin and VEGF-C protein expression with clinicopathological features in breast cancer patients
Variable n Survivin- Survivin+ χ2 p VEGF-C - VEGF-C + χ2 p
Age 0 1 0.965 0.326
≤45 years 36 6 30 6 30
>45 years 72 12 60 18 54
Tumor size 9.305 0.01 4.102 0.129
T1 39 12 27 12 27
T2 60 6 54 9 51
T3 9 0 9 3 6
Histological grade 0.873 0.350 0.175 0.675
I + II 99 15 84 21 78
III 9 3 6 3 6
Pathological style 0.169 0.681 0 1
ISC 12 3 9 3 9
IC 96 15 81 21 75
Lymph node metastasis 16.283 0.000 18.544 0.000
Negative 30 12 18 15 15
Positive 78 6 72 9 69
C-erBb-2 8.269 0.004 4.354 0.037
positive(3 + ) 12 6 6 6 6
negative(0-2 + ) 96 12 84 18 78
ER 0.617 0.432 0.882 0.348
positive 63 9 54 12 51
negative 45 9 36 12 33
PR 0 1 1.929 0.165
positive 54 9 45 15 39
negative 54 9 45 9 45
TNM stage 10.800 0.001 6.027 0.014
I, II 72 18 54 21 51
III, IV 36 0 36 3 33

ISC, in situ carcinoma; IC, invasive carcinoma.

Cai et al.

Cai et al. Diagnostic Pathology 2012 7:52   doi:10.1186/1746-1596-7-52

Open Data