Expression of survivin and VEGF-C in different processed cells at protein and mRNA level.a and b: western blot analysis for protein expression; c and d: real-time PCR for mRNA expresison. * means statistically significant decrease comparing to 30, and ** means statistically significant increase comparing to 30 (both p<0.05). (30 = ZR-75-30 breast cancer cell line; p-N = plasmid with negative control; lv-N = lentivirus with negative control; p-S = survivin shRNA; p-V = VEGF-C shRNA; lv-S = lentivirus with survivin gene).
Cai et al. Diagnostic Pathology 2012 7:52 doi:10.1186/1746-1596-7-52