Figure 1.

Manual and automated annotations of ovarian serous carcinoma. Ovarian serous carcinoma TMA spots immunohistochemically stained for S100A1. Representative lowly and highly stained spots are shown (A-B). Image data were processed by both manual pathologist-supervised hand annotations and automated Genie Histology Pattern Recognition software. Digital hand annotations are presented as green outlines of carcinoma, excluding stroma and minimizing background and glass (C-D). These same TMA spots were classified by Genie as carcinoma (dark blue), stroma (yellow), and glass (light blue) (E-F).

Rizzardi et al. Diagnostic Pathology 2012 7:42   doi:10.1186/1746-1596-7-42
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