Table 3

Multivariate analysis of the association between prognosis and various clinicopathologic parameters in patients with PGC

Features

Overall survival

Disease-free survival

Hazard ratio

95% CI

P

Hazard ratio

95% CI

P

Pathologic T stage (T1± T2 vs. T3 ± T4)

0.528

0.106-5.291

NS

1.066

0.281-6.893

NS

Clinical stage (I± II vs. III ± IV)

8.862

1.328-26.523

0.008

3.391

1.183-9.923

0.02

Nodal metastasis (Negative vs. Positive)

1.728

0.553-6.965

NS

1.625

0.685-7.097

NS

Distant metastasis (Negative vs. Positive)

1.763

1.128-6.553

NS

1.711

0.737-7.267

NS

Venous/lymphatic invasion (Negative vs. Positive)

2.181

1.018-8.106

NS

2.527

1.023-8.298

NS

Perineural invasion (Negative vs. Positive)

0.826

0.115-3.089

NS

0.908

0.259-3.765

NS

SOX4 expression (Negative vs. Positive)

3.682

1.102-10.282

0.03

2.215

1.088-7.016

0.04

Note: 'NS' refers to 'No statistic significance'

Wang et al. Diagnostic Pathology 2012 7:41   doi:10.1186/1746-1596-7-41