Table 2

Univariate analysis of the association between prognosis and various clinicopathologic parameters in patients with PGC

Features

Overall survival

Disease-free survival

Hazard ratio

95% CI

P

Hazard ratio

95% CI

P

Gender (Male vs. Female)

0.672

0.328-1.296

NS

1.007

0.426-2.335

NS

Age (≤ 66 years vs.≥ 66 years)

0.766

0.357-1.402

NS

0.890

0.368-1.563

NS

Tumor size (≤ 2.5 cm vs.≥ 2.5 cm)

0.819

0.334-1.628

NS

1.023

0.269-2.682

NS

Histological grade (G1-G2 vs. G3± G4)

0.981

0.365-2.879

NS

1.107

0.319-2.989

NS

Pathologic T stage (T1± T2 vs. T3 ± T4)

3.387

1.528-8.336

0.008

3.072

1.269-8.668

0.02

Clinical stage (I± II vs. III ± IV)

5.620

1.591-11.072

< 0.001

4.863

1.893-10.651

0.001

Nodal metastasis (Negative vs. Positive)

4.701

1.310-8.543

0.001

4.663

1.700-10.253

0.001

Distant metastasis (Negative vs. Positive)

4.509

1.271-9.775

0.001

2.181

1.037-4.357

NS

Venous/lymphatic invasion (Negative vs. Positive)

2.687

1.190-5.053

NS

2.508

1.431-4.383

NS

Perineural invasion (Negative vs. Positive)

1.216

1.087-3.126

NS

1.246

1.507-3.608

NS

SOX4 expression (Negative vs. Positive)

3.237

1.221-7.952

0.01

3.782

1.339-8.862

0.02

Note: 'NS' refers to 'No statistic significance'

Wang et al. Diagnostic Pathology 2012 7:41   doi:10.1186/1746-1596-7-41