Table 1 |
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|
Association of SOX4 expression with the clinicopathological features of 136 patients with PGC |
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|
Factor |
NO. |
SOX4 expression (n, %) |
P |
|||
|
|
||||||
|
Negative |
Weak |
Moderate |
Strong |
|||
|
|
||||||
|
Gender |
||||||
|
Male |
60 |
14 (23.3) |
9 (15.0) |
20 (33.3) |
17 (28.3) |
NS |
|
Female |
76 |
20 (22.2) |
12 (15.8) |
25 (32.9) |
19 (25.0) |
|
|
Age |
||||||
|
≤ 66 years |
65 |
16 (24.6) |
10 (15.4) |
21 (32.3) |
18 (27.7) |
NS |
|
> 66 years |
71 |
18 (25.4) |
11 (15.5) |
24 (33.8) |
18 (25.4) |
|
|
Tumor size |
||||||
|
≤ 2.5 cm |
72 |
19 (26.4) |
12 (16.7) |
25 (34.7) |
16 (22.2) |
NS |
|
> 2.5 cm |
64 |
15 (23.4) |
9 (14.1) |
20 (31.3) |
20 (31.3) |
|
|
Histological grade |
||||||
|
G1 |
18 |
1 (5.6) |
3 (16.7) |
4 (22.2) |
10 (55.6) |
0.02 |
|
G2 |
72 |
13 (18.1) |
3 (4.2) |
32 (44.4) |
24 (33.3) |
|
|
G3 |
33 |
10 (30.3) |
13 (39.4) |
8 (24.2) |
2 (6.1) |
|
|
G4 |
13 |
10 (76.9) |
2 (15.4) |
1 (7.7) |
0 (0.0) |
|
|
Pathologic T stage |
||||||
|
T1 |
22 |
2 (9.1) |
2 (9.1) |
6 (27.3) |
12 (54.5) |
0.02 |
|
T2 |
60 |
4 (6.7) |
5 (8.3) |
29 (48.3) |
22 (36.7) |
|
|
T3 |
36 |
16 (44.4) |
10 (27.8) |
8 (22.2) |
2 (5.6) |
|
|
T4 |
18 |
12 (66.7) |
4 (22.2) |
2 (11.1) |
0 (0.0) |
|
|
Clinical stage |
||||||
|
I |
46 |
4 (8.7) |
6 (13.0) |
16 (2.2) |
20 (43.5) |
0.03 |
|
II |
52 |
8 (15.4) |
4 (7.7) |
25 (48.1) |
15 (28.8) |
|
|
III |
18 |
10 (55.6) |
5 (27.8) |
2 (11.1) |
1 (5.6) |
|
|
IV |
20 |
12(60.0) |
6 (30.0) |
2 (10.0) |
0 (0.0) |
|
|
Nodal metastasis |
||||||
|
Negative |
92 |
12 (13.0) |
3 (3.3) |
41 (44.6) |
36 (39.1) |
0.01 |
|
Positive |
44 |
22 (50.0) |
18 (40.9) |
4 (9.1) |
0 (0.0) |
|
|
Distant metastasis |
||||||
|
Negative |
112 |
28 (25.0) |
16 (14.3) |
35 (31.3) |
33 (29.5) |
NS |
|
Positive |
24 |
6 (25.0) |
5 (20.8) |
10 (41.7) |
3 (12.5) |
|
|
Venous/lymphatic invasion |
||||||
|
Negative |
82 |
22 (26.8) |
12 (14.6) |
24 (29.3) |
24 (29.3) |
NS |
|
Positive |
54 |
12 (22.2) |
9 (16.7) |
21 (38.9) |
12 (22.2) |
|
|
Perineural invasion |
||||||
|
Negative |
79 |
20 (25.3) |
12 (15.2) |
24 (30.4) |
23 (29.1) |
NS |
|
Positive |
57 |
14 (24.6) |
9 (15.8) |
21 (36.8) |
13 (22.8) |
|
|
|
||||||
|
Note: 'NS' refers to 'No statistic significance' |
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|
Wang et al. Diagnostic Pathology 2012 7:41 doi:10.1186/1746-1596-7-41 |
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