Table 2

TERC and C-MYC positivity rates for various histological diagnoses

Histological diagnosis

Case no.

TERC positive

C-MYC positive

Case no.

%

P

Case no.

%

P

Normal

164

15

9.2

34

20.7

CIN1†

29

5

17.2

9

31.0

CIN2

21

16

76.2

15

71.4

CIN3

22

22

100.0

18

81.8

SCC

7

7

100.0

7

100.0

Normal vs. CIN1

> 0.05

> 0.05

CIN1 vs. CIN2+

< 0.01*

< 0.01*

Normal/CIN1 vs. CIN2+

< 0.01*

< 0.01*

† CIN1 includes lesions previously classified as mild dysplasia, koilocytotic atypia, koilocytosis and flat condyloma

* P < 0.05: statistically significant difference between 2 categories

Chen et al. Diagnostic Pathology 2012 7:40   doi:10.1186/1746-1596-7-40