Figure 3.

ROC and DFI curves for aberrant cell percentage and maximum GCN of TERC and C-MYC gain for CIN2+ diagnosis. A: Plots of sensitivity vs. 1-specificity at cut-off values of the percentage of aberrant cells and of maximum GCN for the TERC and C-MYC tests. B: Plots of DFI vs. cut-off values of the percentage of aberrant cells of the TERC and C-MYC tests. C: Plots of DFI vs. cut-off values at maximum GCN of the TERC and C-MYC tests. In A, B and C, blue diamonds indicate the results of TERC gain at cut-off values of aberrant cell percentage ranging from 0% to 100%; pink squares indicate the results of C-MYC gain at cut-off values of aberrant cell percentage ranging from 0% to 100%; orange diamonds indicate the results of TERC gain at cut-off values of GCN ranging from 1 to 23; slate green squares indicate the results of C-MYC gain at cut-off values of GCN ranging from 1 to 13.