Table 1

The correlation between the expression of HIF-2 alpha and BCRP, the clinicopathological parameter

Patients n (%)

HIF-2 alpha expression

P value


negative

low

high


ABCG2 expression

0.001*

negative

26

8

17

1

low

97

12

58

27

high

73

5

39

29


Age

0.053


≤ 50 years

80

10

54

16


> 50 years

116

15

60

41


Histology-type

0.285


IDC

155

22

86

47


IDC with others

41

3

28

10


Histology-grade

0.029*


G1/G2

143

16

78

49


G3

53

9

36

8


Tumour size

0.601


≤2.0 cm

97

13

53

31


> 2.0 cm

99

12

61

26


LNM

0.808


-

103

13

58

32


+

93

12

56

25


ER

0.544


-/+

96

10

59

27


++/+++

100

15

55

30


PR

0.343


-/+

128

14

79

35


++/+++

68

11

35

22


HER2

0.923


-/+

138

18

81

39


++/+++

58

7

33

18


Ki67

0.043*


Positive ≤50%

154

20

83

51


Positive > 50%

42

5

31

6


Clinical stage

0.538


Stage I

60

7

33

20


Stage IIa and IIb

86

13

47

26


StageIIIa and IIIb

50

5

34

11


P values were evaluated by chi-square test or the Fisher's exact test. *P < 0.05

Xiang et al. Diagnostic Pathology 2012 7:32   doi:10.1186/1746-1596-7-32

Open Data