Table 1

The correlation between the expression of HIF-2 alpha and BCRP, the clinicopathological parameter

Patients n (%)

HIF-2 alpha expression

P value

negative

low

high

ABCG2 expression

0.001*

negative

26

8

17

1

low

97

12

58

27

high

73

5

39

29

Age

0.053

≤ 50 years

80

10

54

16

> 50 years

116

15

60

41

Histology-type

0.285

IDC

155

22

86

47

IDC with others

41

3

28

10

Histology-grade

0.029*

G1/G2

143

16

78

49

G3

53

9

36

8

Tumour size

0.601

≤2.0 cm

97

13

53

31

> 2.0 cm

99

12

61

26

LNM

0.808

-

103

13

58

32

+

93

12

56

25

ER

0.544

-/+

96

10

59

27

++/+++

100

15

55

30

PR

0.343

-/+

128

14

79

35

++/+++

68

11

35

22

HER2

0.923

-/+

138

18

81

39

++/+++

58

7

33

18

Ki67

0.043*

Positive ≤50%

154

20

83

51

Positive > 50%

42

5

31

6

Clinical stage

0.538

Stage I

60

7

33

20

Stage IIa and IIb

86

13

47

26

StageIIIa and IIIb

50

5

34

11

P values were evaluated by chi-square test or the Fisher's exact test. *P < 0.05

Xiang et al. Diagnostic Pathology 2012 7:32   doi:10.1186/1746-1596-7-32