Table 4 |
||||||
|
Impact of potential prognostic factors on DFS of patients of lung adenocarcinoma in p-stage I by univariate and multivariate analysis |
||||||
|
No. |
% |
Univariate Analysis |
Multivariate analysis |
|||
|
|
|
|||||
|
P value |
Hazard ratio |
95% CI |
P value |
|||
|
|
||||||
|
Total |
458 |
|||||
|
Age |
||||||
|
< 65 |
172 |
38 |
0.394 |
1.000 |
||
|
≥ 65 |
286 |
62 |
2.191 |
0.474-10.131 |
0.316 |
|
|
Gender |
||||||
|
Female |
249 |
54 |
0.063 |
1.000 |
||
|
Male |
209 |
46 |
0.157 |
0.014-1.787 |
0.136 |
|
|
Smoking status |
||||||
|
Non-smoker |
248 |
54 |
0.204 |
1.000 |
||
|
Smoker |
210 |
46 |
0.768 |
0.117-5.052 |
0.784 |
|
|
Tumor size |
||||||
|
< 30 mm |
358 |
78 |
0.264 |
1.000 |
||
|
≥ 30 mm |
100 |
22 |
0.304 |
0.037-2.504 |
0.268 |
|
|
Pleural invasion |
||||||
|
Negative |
402 |
88 |
< 0.001 |
1.000 |
||
|
Positive |
56 |
12 |
1.519 |
0.328-7.040 |
0.593 |
|
|
Lymphatic invasion |
||||||
|
Negative |
415 |
91 |
< 0.001 |
1.000 |
||
|
Positive |
43 |
9 |
5.016 |
1.295-19.434 |
0.020 |
|
|
Vascular invasion |
||||||
|
Negative |
390 |
85 |
< 0.001 |
1.000 |
||
|
Positive |
68 |
15 |
4.494 |
1.006-20.081 |
0.049 |
|
|
SMPC |
||||||
|
Negative |
448 |
98 |
< 0.001 |
1.000 |
||
|
Positive |
10 |
2 |
9.028 |
1.164-70.031 |
0.035 |
|
|
AMPC |
||||||
|
Negative |
389 |
98 |
0.023 |
1.000 |
||
|
Positive |
69 |
2 |
1.825 |
0.378-8.808 |
0.454 |
|
|
|
||||||
|
DFS, disease free survival; No., number of patients; SMPC, stromal micropapillary component; AMPC, aerogeneous micropapillary component; CI, confidence interval. |
||||||
|
Ohe et al. Diagnostic Pathology 2012 7:3 doi:10.1186/1746-1596-7-3 |
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