Table 3 |
||||||
|
Impact of potential prognostic factors on DFS of patients of lung adenocarcinoma in all stage by univariate and multivariate analysis |
||||||
|
No. |
% |
Univariate analysis |
Multivariate analysis |
|||
|
|
|
|||||
|
P value |
Hazard ratio |
95% CI |
P value |
|||
|
|
||||||
|
Total |
559 |
|||||
|
Age |
||||||
|
< 65 |
213 |
38 |
0.388 |
1.000 |
||
|
≥ 65 |
346 |
62 |
1.933 |
0.849-4.402 |
0.116 |
|
|
Gender |
||||||
|
Female |
288 |
52 |
0.768 |
1.000 |
||
|
Male |
271 |
48 |
0.807 |
0.232-2.803 |
0.735 |
|
|
Smoking status |
||||||
|
Non-smoker |
284 |
49 |
0.560 |
1.000 |
||
|
Smoker |
275 |
51 |
1.164 |
0.342-3.956 |
0.808 |
|
|
Tumor size |
||||||
|
< 30 mm |
396 |
71 |
0.059 |
1.000 |
||
|
≥ 30 mm |
163 |
29 |
0.819 |
0.338-1.985 |
0.658 |
|
|
Pathological stage |
||||||
|
I |
458 |
82 |
<0.001 |
1.000 |
||
|
II, III, IV |
101 |
18 |
2.768 |
1.113-6.884 |
0.028 |
|
|
Pleural invasion |
||||||
|
Negative |
452 |
81 |
<0.001 |
1.000 |
||
|
Positive |
107 |
19 |
0.848 |
0.345-2.083 |
0.719 |
|
|
Lymphatic invasion |
||||||
|
Negative |
466 |
83 |
<0.001 |
1.000 |
||
|
Positive |
93 |
17 |
3.430 |
1.363-8.634 |
0.009 |
|
|
Vascular invasion |
||||||
|
Negative |
427 |
76 |
<0.001 |
1.000 |
||
|
Positive |
132 |
24 |
3.309 |
1.312-8.350 |
0.011 |
|
|
SMPC |
||||||
|
Negative |
540 |
97 |
<0.001 |
1.000 |
||
|
Positive |
19 |
3 |
1.871 |
0.528-6.630 |
0.332 |
|
|
AMPC |
||||||
|
Negative |
460 |
83 |
0.045 |
1.000 |
||
|
Positive |
99 |
17 |
1.132 |
0.450-2.845 |
0.792 |
|
|
|
||||||
|
DFS, disease free survival; No., number of patients; SMPC, stromal micropapillary component; AMPC, aerogeneous micropapillary component; CI, confidence interval. |
||||||
|
Ohe et al. Diagnostic Pathology 2012 7:3 doi:10.1186/1746-1596-7-3 |
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