Table 3

Impact of potential prognostic factors on DFS of patients of lung adenocarcinoma in all stage by univariate and multivariate analysis

No.

%

Univariate

analysis

Multivariate analysis



P value

Hazard ratio

95% CI

P value


Total

559

Age

< 65

213

38

0.388

1.000

≥ 65

346

62

1.933

0.849-4.402

0.116

Gender

Female

288

52

0.768

1.000

Male

271

48

0.807

0.232-2.803

0.735

Smoking status

Non-smoker

284

49

0.560

1.000

Smoker

275

51

1.164

0.342-3.956

0.808

Tumor size

< 30 mm

396

71

0.059

1.000

≥ 30 mm

163

29

0.819

0.338-1.985

0.658

Pathological stage

I

458

82

<0.001

1.000

II, III, IV

101

18

2.768

1.113-6.884

0.028

Pleural invasion

Negative

452

81

<0.001

1.000

Positive

107

19

0.848

0.345-2.083

0.719

Lymphatic invasion

Negative

466

83

<0.001

1.000

Positive

93

17

3.430

1.363-8.634

0.009

Vascular invasion

Negative

427

76

<0.001

1.000

Positive

132

24

3.309

1.312-8.350

0.011

SMPC

Negative

540

97

<0.001

1.000

Positive

19

3

1.871

0.528-6.630

0.332

AMPC

Negative

460

83

0.045

1.000

Positive

99

17

1.132

0.450-2.845

0.792


DFS, disease free survival; No., number of patients; SMPC, stromal micropapillary component; AMPC, aerogeneous micropapillary component; CI, confidence interval.

Ohe et al. Diagnostic Pathology 2012 7:3   doi:10.1186/1746-1596-7-3

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