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Open Access Case Report

Renal cell carcinoma associated with peritumoral sarcoid-like reaction without intratumoral granuloma

Simon Ouellet1, Roula Albadine2 and Robert Sabbagh1*

Author Affiliations

1 Department of Surgery, Division of Urology, Sherbrooke University, Centre hospitalier universitaire de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC J1H 5N4, Canada

2 Department of Pathology, Sherbrooke University, Centre hospitalier universitaire de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC J1H 5N4, Canada

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Diagnostic Pathology 2012, 7:28  doi:10.1186/1746-1596-7-28

Published: 18 March 2012

Abstract

Non-necrotizing epithelioid granulomas have been described in association with many primary tumors. In such cases, they are designated as sarcoid-like reaction. Although it is more seen in carcinomas than in sarcomas, it is very rarely reported in renal carcinoma. Here, we describe a rare association of prominent peritumoral sarcoid-like reaction without intratumoral granulomas and conventional clear cell renal carcinoma in a 62-year-old-male, without clinical or laboratory finding of sarcoidosis. At 30 months follow-up, he had no recurrence.

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Keywords:
Sarcoid-like reaction; Granuloma; Renal cell carcinoma