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Open Access Case Report

Pleural malakoplakia caused by Rhodoccocus equi infection in a patient after stem cell transplantation

Carl Ludwig Behnes1*, Silke Neumann2, Stefan Schweyer1 and Heinz-Joachim Radzun1

Author affiliations

1 Department of Pathology, University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany

2 Department of Oncology, University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany

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Citation and License

Diagnostic Pathology 2012, 7:20  doi:10.1186/1746-1596-7-20

Published: 23 February 2012

Abstract

Malakoplakia is a disease especially of the urinary tract with typical plaques most frequently observed in the urinary bladder's mucosa. In the context of immunosuppression malakoplakia can also occur in other organs. Some of these extravesical malakoplakias are associated with an infection by Rhodococcus equi, a rare human pathogen well known from veterinary medicine. Here we present the first case of a pleural malakoplakia without lung involvement caused by a proved Rhodococcus equi infection.

Keywords:
Malakoplakia; Pleura; Rhodococcus equi; Michaelis-Gutmann-Bodies