Cytomorphologic examination of the bronchial brushing cytology specimens. (A) The cytology specimens were consisted of many clusters of cohesive and sheet-like or three-dimensional tumor cells and a small number of individual tumor cells without necrotic or hemorrhagic backgrounds (Papanicolaou stains). Bar = 25 μm. (B) Those malignant cells showed small to medium-sized (12 to 20 μm in diameter), relatively uniform, and round to oval with mild pleomorphism and had relatively scanty cytoplasm. Additionally, the nuclei were hyperchromatic, predominantly in a coarsely granular chromatin pattern, and had inconspicuous nucleoli but mitotic figures (arrowhead) (Papanicolaou stains). Rosettes were absent. Bar = 25 μm.
Yamada et al. Diagnostic Pathology 2012 7:175 doi:10.1186/1746-1596-7-175