|
Resolution: standard / high Figure 4.
Immunohistochemically, the carcinoma cells are clearly positive for CK7 (a), ER (b),
while many stromal cells show positive reaction for inhibin-α (c) (Case 3). Expression
of steroid factor-1 (SF-1), which is a transcription factor alternatively termed adrenal
4-binding protein (Ad4BP) to regulate expression of all steroidogenic enzymes [9], is predominant in the stromal cells but minimal in epithelial cells (Case 1).
Katoh et al. Diagnostic Pathology 2012 7:164 doi:10.1186/1746-1596-7-164 |