Table 2

Demographics and patients’ characteristics according to diagnosis by interdisciplinary evaluation
All IPF/UIP NSIP RBILD COP HP LCH
Patients (N) 74 27 14 6 10 10 7
Gender,male/female 43/31 21/6 6/8 5/1* 7/3 2/8** 2/5
Age, mean ± SE 53 ± 11 60 ± 11 51 ± 14* 44 ± 6* 58 ± 11 52 ± 10 44 ± 12*
BMI, kg/m2 26 ± 5 28 ± 5 26 ± 4 26 ± 4 26 ± 4 24 ± 3 24 ± 8**
Smoking history
  - current/ex (%) 47 (64) 18 (67) 8 (57) 6 (100)* 7 (70) 1 (10) 7 (100)*
  - never smokers 27 (36) 9 (33) 6 (43) 0 (0) 3 (30) 9 (90) 0 (0)
Pack years, mean 20.4 17 14.5 27 21 n.a. 22.5
Symptoms
  - dyspnoea (%) 65 (88) 26 (96) 13 (93) 4 (67) 7 (70) 10 (100) 5 (71)
  - cough (%) 54 (73) 22 (78) 9 (64) 3 (50) 8 (80) 8 (80) 4 (57)
Duration of symptoms, years 2.2 1.6 1.7†† 1.4 0.3†† 4.3** 4.2**
FVC % pred, mean ± SE 66 ± 15 61 ± 16 61 ± 9 71 ± 7 72 ± 11 57 ± 13 78 ± 19**
FEV1, % pred, mean ± SE 66 ± 14 66 ± 15 65 ± 12 77 ± 12 77 ± 13 63 ± 14 54 ± 21†
TLC, % pred, mean ± SE 78 ± 20 67 ± 14 77 ± 15 91 ± 15* 85 ± 19* 68 ± 10 98 ± 17*
PaO2, mmHg 74 ± 10 73 ± 8 73 ± 8 80 ± 8 70 ± 14 78 ± 10 72 ± 13
PaCO2, mmHg 38 ± 4 39 ± 4 36 ± 3 39 ± 3 40 ± 5 39 ± 3 37 ± 4
AaDO2, mmHg 28 ± 16 33 ± 19 30 ± 11 13 ± 6** 25 ± 12 22 ± 10 16 ± 7

n.a. = not available.

* p <0.005 vs IPF/UIP.

** p < 0.05 vs IPF/UIP.

† p < 0.05 vs RBILD and COP.

†† p < 0.05 vs HP and LCH.

Theegarten et al.

Theegarten et al. Diagnostic Pathology 2012 7:160   doi:10.1186/1746-1596-7-160

Open Data