Table 2 |
|||||||
| Demographics and patients’ characteristics according to diagnosis by interdisciplinary evaluation | |||||||
| All | IPF/UIP | NSIP | RBILD | COP | HP | LCH | |
| Patients (N) | 74 | 27 | 14 | 6 | 10 | 10 | 7 |
| Gender,male/female | 43/31 | 21/6 | 6/8 | 5/1* | 7/3 | 2/8** | 2/5 |
| Age, mean ± SE | 53 ± 11 | 60 ± 11 | 51 ± 14* | 44 ± 6* | 58 ± 11 | 52 ± 10 | 44 ± 12* |
| BMI, kg/m2 | 26 ± 5 | 28 ± 5 | 26 ± 4 | 26 ± 4 | 26 ± 4 | 24 ± 3 | 24 ± 8** |
| Smoking history | |||||||
| - current/ex (%) | 47 (64) | 18 (67) | 8 (57) | 6 (100)* | 7 (70) | 1 (10) | 7 (100)* |
| - never smokers | 27 (36) | 9 (33) | 6 (43) | 0 (0) | 3 (30) | 9 (90) | 0 (0) |
| Pack years, mean | 20.4 | 17 | 14.5 | 27 | 21 | n.a. | 22.5 |
| Symptoms | |||||||
| - dyspnoea (%) | 65 (88) | 26 (96) | 13 (93) | 4 (67) | 7 (70) | 10 (100) | 5 (71) |
| - cough (%) | 54 (73) | 22 (78) | 9 (64) | 3 (50) | 8 (80) | 8 (80) | 4 (57) |
| Duration of symptoms, years | 2.2 | 1.6 | 1.7†† | 1.4 | 0.3†† | 4.3** | 4.2** |
| FVC % pred, mean ± SE | 66 ± 15 | 61 ± 16 | 61 ± 9 | 71 ± 7 | 72 ± 11 | 57 ± 13 | 78 ± 19** |
| FEV1, % pred, mean ± SE | 66 ± 14 | 66 ± 15 | 65 ± 12 | 77 ± 12 | 77 ± 13 | 63 ± 14 | 54 ± 21† |
| TLC, % pred, mean ± SE | 78 ± 20 | 67 ± 14 | 77 ± 15 | 91 ± 15* | 85 ± 19* | 68 ± 10 | 98 ± 17* |
| PaO2, mmHg | 74 ± 10 | 73 ± 8 | 73 ± 8 | 80 ± 8 | 70 ± 14 | 78 ± 10 | 72 ± 13 |
| PaCO2, mmHg | 38 ± 4 | 39 ± 4 | 36 ± 3 | 39 ± 3 | 40 ± 5 | 39 ± 3 | 37 ± 4 |
| AaDO2, mmHg | 28 ± 16 | 33 ± 19 | 30 ± 11 | 13 ± 6** | 25 ± 12 | 22 ± 10 | 16 ± 7 |
n.a. = not available.
* p <0.005 vs IPF/UIP.
** p < 0.05 vs IPF/UIP.
† p < 0.05 vs RBILD and COP.
†† p < 0.05 vs HP and LCH.
Theegarten et al. Diagnostic Pathology 2012 7:160 doi:10.1186/1746-1596-7-160
