Left side (A, C, E, G): Curves derived from different measures performed on 4 tumors. Right side (B, D, F, H): Different pattern of lymphocytic infiltration defined according to the mean curve derived from the different measures in A, C, E and G respectively. Pattern 1: High density of positive lymphocytes within the tumors (A, B). Pattern 2: High Peak of lymphocyte density within the non-tumorous tissues localized nearby the tumors (C, D) and Low Peak of lymphocyte density within the non-tumorous tissues localized nearby the tumors (E, F). Pattern 3: Uniform low lymphocyte density (G, H).
Allard et al. Diagnostic Pathology 2012 7:156 doi:10.1186/1746-1596-7-156