Figure 1.

a: Primary bladder adenocarcinoma, enteric type. Moderately differentiated malignant glands are seen with dirty luminal necrosis. Elongated, enlarged and hyperchromatic nuclei with prominent stratification line the malignant glands. (Hematoxylin & eosin, x100). b: Primary bladder adenocarcinoma, mucinous type. Scattered small groups of tumor cells with intracytoplasmic mucin are seen in a background of abundant mucinous material (Hematoxylin & eosin, x200). c: Primary bladder adenocarcinoma, signet ring cell type: Tumor comprised of diffuse sheets of signet ring cells infiltrating the bladder wall (Hematoxylin & eosin, x200). d: Cystitis cystica involving the surface urothelium with underlying invasive primary bladder adenocarcinoma (Hematoxylin & eosin, x100). e: Extensive cystitis glandularis, intestinal type seen adjacent to a focus of invasive primary bladder adenocarcinoma (not seen in this image) (Hematoxylin & eosin, x40). f: Metastatic colorectal adenocarcinoma. Moderately differentiated, infiltrating malignant glands with morphological features similar to primary bladder adenocarcinoma see in a (Hematoxylin & eosin, x100).

Roy et al. Diagnostic Pathology 2012 7:151   doi:10.1186/1746-1596-7-151
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