Table 1

Expression of MMP-2 and TIMP-1 in the renal tissue and serum creatinine in groups with different degrees of interstitial fibrosis and tubular atrophy and normal controls (Mean ± SD)
Groups N MMP-2 (%) TIMP-1 (%) Scrum (umol/L)
Normal controls 15 8.10 ± 4.41 9.02 ± 5.64 87.32 ± 2.38
IF/TA-I 16 39.52 ± 8.91 22.21 ± 12.62 175.81 ± 41.53
IF/TA-II 14 23.85 ± 5.25※▲ 36.38 ± 13.12※▲ 327.07 ± 102.14※▲
IF/TA-III 16 15.55 ± 4.16※▲◆ 51.58 ± 12.75※▲◆ 535.42 ± 123.20※▲◆

※:P<0.05, vs Control Group; ▲:P<0.05, vs IF/TA-IGroup; ◆:P<0.05. vs IF/TA-IIGroup.

Yan et al.

Yan et al. Diagnostic Pathology 2012 7:141   doi:10.1186/1746-1596-7-141

Open Data