Table 1 |
||||
| Expression of MMP-2 and TIMP-1 in the renal tissue and serum creatinine in groups with different degrees of interstitial fibrosis and tubular atrophy and normal controls (Mean ± SD) | ||||
| Groups | N | MMP-2 (%) | TIMP-1 (%) | Scrum (umol/L) |
| Normal controls | 15 | 8.10 ± 4.41 | 9.02 ± 5.64 | 87.32 ± 2.38 |
| IF/TA-I | 16 | 39.52 ± 8.91※ | 22.21 ± 12.62※ | 175.81 ± 41.53※ |
| IF/TA-II | 14 | 23.85 ± 5.25※▲ | 36.38 ± 13.12※▲ | 327.07 ± 102.14※▲ |
| IF/TA-III | 16 | 15.55 ± 4.16※▲◆ | 51.58 ± 12.75※▲◆ | 535.42 ± 123.20※▲◆ |
※:P<0.05, vs Control Group; ▲:P<0.05, vs IF/TA-IGroup; ◆:P<0.05. vs IF/TA-IIGroup.
Yan et al. Diagnostic Pathology 2012 7:141 doi:10.1186/1746-1596-7-141
