Table 1

Immunohistochemical staining of Langerhans cell sarcoma
Marker Langerhans cell sarcoma in our case Typical immunophenotype of tumors derived from Langerhans cells
CD1a + +
Langerin + +
S100 + +
CD4 + +
CD3 30-40% + cytoplasm -
p53 + +/−
CD30 30-40% + NK
BCL2 + +
Ki-67 >50% 0-25%
CD5 - -
CD8 - -
CD10 - -
CD20 - -
CD23 - -
CD56 - -
BCL6 - -
MUM-1 - -
Cyclin D1 - -
CD68 - +/−
CD163 - NK
ALK - -

NK: not known.

Xu et al.

Xu et al. Diagnostic Pathology 2012 7:128   doi:10.1186/1746-1596-7-128

Open Data